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https://ace.blog.gov.uk/2022/09/30/tackling-covid-19-using-data-driven-insights-from-wastewater-analysis/

Tackling Covid-19 using data-driven insights from wastewater analysis

Posted by: , Posted on: - Categories: Data, Data science, Healthcare, Innovation

The Accelerated Capability Environment (ACE) exists to tackle urgent operational challenges, and we were asked to bring our planning, technical and data expertise to bear as part of the national effort to tackle Covid-19. 

Early in the pandemic we were approached by the Joint Biosecurity Centre (JBC), now part of the UK Health Security Agency, to help explore the potential of wastewater-based epidemiology (WBE) as an early warning system to help the UK stay ahead of new disease outbreaks. 

Working with the JBC’s Environmental Monitoring for Health Protection team, we were tasked with developing and accelerating innovative solutions across the whole wastewater monitoring cycle.  

The aim was to help design an operating model for a scalable and sustainable national wastewater capability which makes effective use of data for environmental monitoring, health protection and national security purposes, forming part of the UK’s critical national infrastructure. 

To achieve this, ACE lead an extensive and far-reaching body of work. This comprised of: 

  • 32 programmes 
  • 84 discrete projects 
  • 63 suppliers from our Vivace community of industry expertise 

This work focused primarily on accelerating technology and research to increase the quality and range of collected data to provide actionable insights. By thinking differently, and approaching the problem with fresh thinking, we were ultimately able to deliver a proof of concept for end-to-end automation of the entire process. 

Designing change 

Working capabilities demonstrated included: 

  • A SewerSafe app, which uses sewer networks and hydraulic models to identify optimal sampling points. 
  • A mobile testing unit which took laboratory equipment to the point of wastewater sampling to provide results in under four hours, a near twentyfold reduction on typical time taken. 
  • The capability of post-pandemic sensors which will enable wider data analysis. 
  • Near-real-time detection including harnessing quantum nano diamonds to increase the limits of detection using lateral flow type ‘dip-sticks’. 
  • A no-chill transport solution using electronegative filter papers for viral load transportation, providing a cost-effective no-chill solution that has global exploitation potential. 
  • End-to-end automation, realised by developing an innovative robotic system based on a 3D printer. 

 

ACE also conducted several practical trials to assess the ability to localise the source of an infection including at universities and at a city-wide level. A major success was a care homes trial, where Covid-19 was identified in wastewater outside routine testing, leading to the early identification and isolation of those infected, reducing the spread and protecting elderly and vulnerable residents.  

Overall, ACE’s work on the WBE commission delivered £18million of innovation and accelerated technology development for automating on-site detection by three to five years. 

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